Introducing Infinity: DENSsolutions’ pioneering 8-contact environmental in situ solution

Introducing Infinity: DENSsolutions’ pioneering 8-contact environmental in situ solution

An interview with DENSsolutions’ Senior Mechanical Engineer about our latest innovation, Infinity – featuring an environmental holder with combined heating and biasing capabilities in both gas and liquid environments.

In this article, we delve into DENSsolutions’ cutting-edge Infinity solution through an exclusive interview with lead developer and Senior Mechanical Engineer, Christian Deen-van Rossum. Here, Christian takes us through the key features of this innovation, highlighting its benefits, diverse applications, and offering an inside look into the development journey of this advanced solution.

1) What are the main benefits of the Infinity solution for users?

“Climate Infinity and Stream Infinity bring forth numerous advantages for your in situ experiments:

1) Apply simultaneous heating and biasing stimuli: The new Climate/Stream Infinity holder features eight electrical contacts that enable simultaneous application of electrical and thermal stimuli in a gas or liquid environment. The contacts can be used for various electrically driven MEMS-based sensors and actuators, essentially transforming the Infinity system into a vast research playground. Importantly, for liquid studies, this opens the door to performing electrochemistry as a function of temperature.

2) Securely transfer your sample from one microscope to the other: The assembled tip of the Infinity holder containing a Nano-Reactor/Cell works as a cartridge, enabling complementary studies of the same sample using different TEM vendors, namely JEOL or Thermo Fisher Scientific (TFS). These microscopes can either be located in the same TEM lab, user facility or even in different universities/institutes. Remarkably, this removable tip also facilitates multi-modal characterization for SEM and beamline setups. Furthermore, the chips being used are universal, meaning that you can directly correlate experimental results obtained from JEOL and TFS microscopes, with improved Nano-Chip logistics.

3) Easily switch between STEM and TEM mode: By flipping the tip 180 degrees, you can directly change the sample position to be either on the top or bottom without a need to disassemble the tip. This grants you the freedom to flawlessly switch between STEM or TEM mode, respectively, depending on your experimental needs, while maintaining the best resolution performance. Importantly, you can switch between both imaging modes within a matter of seconds.

4) Perform gas and liquid studies with the same holder: The new environmental Infinity holder is your all-in-one solution for both gas and liquid experiments. Simply choose the appropriate function for the chips and connect the necessary gas or liquid supply system. Our extensive range of chip types includes gas-heating (GH), liquid-heating (LH), gas-heating-biasing (GHB), and liquid-heating-biasing (LHB), offering unparalleled versatility for your experimental needs. New MEMS chip designs will further expand the application space of the Infinity system.

5) Ease of use: We understand that a great product should be easy to use without a steep learning curve. Therefore, our design process focused on making sure the holder can be effortlessly utilized from the start. By prioritizing user-friendly design and continuously testing with real users, we ensured our product is not only powerful and effective but also simple and enjoyable to use. Because of this, the Infinity holder significantly reduces the time-to-experiment, allowing you to spend your time leveraging its capabilities to drive innovation and productivity. One highlight of the Infinity holder is the removal of all assembly tools and the introduction of self-aligning windows. When you place our chips in the tip of the holder, the membranes automatically align to provide a consistently clear field of view. Designed for a perfect fit, the Infinity holder ensures precise alignment without manual adjustments. This simplifies installation, reduces the risk of leaks, and allows you to focus more on your research and less on setup.

2) What inspired the development of Infinity, and what challenges did you encounter during the process?

“We wanted to bring a better, future-proof and more user-friendly holder to the market that truly meets the needs of our customers. For that reason we developed a holder from a customer-centric approach, driven by extensive customer input and thorough market research, rather than simply pushing the latest technology. We engaged with our customers to understand their challenges and desires and gathered invaluable feedback that helped shape every aspect of our product. By doing this we made sure that we were addressing real pain points and delivering solutions that would help improve the customer experience and reduce time to experiment. This customer-focused approach means that our product is not just a collection of the latest technological advancements, but a thoughtfully designed solution that reflects the actual needs and desires of our users.” 

3) What are the main application fields that will benefit from Climate Infinity and Stream Infinity?

“The Infinity system can be used for broad applications ranging from materials science to energy and life science. In materials science, the Infinity system enables the study of nucleation, growth, assembly and corrosion under well-defined chemical environments (gas, vapor and liquid) and external stimuli (heating, biasing or both). The information obtained not only provides insights into the dynamic processes of material formation but also offers guidelines for the controllable synthesis of materials with improved performance. In energy studies, the Infinity system can mimic the real working conditions of various functional devices (such as batteries, supercapacitors, fuel cells, memristors, resistive random access memory, etc.). This allows the direct monitoring of the evolution and degradation of key materials, including rechargeable battery electrodes, thermo-, electro- and thermoelectro-catalysts and phase-change materials, at the nano- or even atomic scale. For life science, it is possible to image whole cells and resolve fine structures of biomaterials and proteins in their native state, and study various dynamics of biological samples in an environment close to a real organism. Moreover, the Infinity system provides a unique platform for correlative studies across different detection sources, such as electron, X-ray, neutron and visible light.”

4) Has Infinity already been installed?

“Yes, the system has been installed at numerous sites already, including EMAT (Antwerpen, Belgium), FAU Erlangen-Nurnberg (Erlangen, Germany) and UC Irvine (Irvine, USA).”

Dr. Mingjian Wu from FAU Erlangen-Nürnberg

From left to right: Dr. Alexander Zintler from EMAT and Christian Deen van Rossum from DENSsolutions

From left to right: Dr. Hongkui Zheng and Dr. Hongyu Sun from DENssolutions, as well as Pushp Raj Prasad, Prof. Joe Patterson, Zhaoxu Li and Elmira Baghdadi from UC Irvine

Dr. Mingjian Wu from FAU Erlangen-Nürnberg

From left to right: Dr. Alexander Zintler from EMAT and Christian Deen van Rossum from DENSsolutions

From left to right: Dr. Hongkui Zheng and Dr. Hongyu Sun from DENssolutions, as well as Pushp Raj Prasad, Prof. Joe Patterson, Zhaoxu Li and Elmira Baghdadi from UC Irvine

Read more about Climate Infinity:

 

Read more about Stream Infinity:

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Meet our new Senior Operations Manager – Carl Hansen

Meet our new Senior Operations Manager – Carl Hansen

We are excited to announce the expansion of our team with a new wonderful colleague: Carl Hansen.

DENSsolutions Eva Bladt

We recently welcomed Carl Hansen to the DENSsolutions family, whose addition underscores our unwavering commitment to innovation and excellence. Stepping into the role of Senior Operations Manager, Carl brings a wealth of experience and expertise to oversee and optimize various operational facets at DENSsolutions. With a comprehensive background in supply chain management, Carl’s responsibilities encompass leading our Operations team, refining logistics processes and ensuring operational efficiency to support our strategic objectives. By leveraging new technologies and fostering strong collaborations with key stakeholders, Carl’s overarching goal is to establish a world-class operational framework aimed at maximizing efficiency and transforming our supply chain into a strategic asset, driving DENSsolutions’ growth and competitiveness in the market. In this article, we invite you to learn more about Carl’s background, education, experience and pivotal role at DENSsolutions.

Get to know Carl: Personally

“My name is Carl Hansen, and I was born in 1986 in Minnesota, the United States,  but I grew up in Marietta, Georgia just outside of Atlanta. In 2010, I moved to Quito, Ecuador to finalize my MBA and later moved to Bogota, Colombia on 2012 where I met my lovely wife Lina. Together we moved to the Netherlands in 2014. In August 2023 I was naturalized as a Dutch citizen, making me a dual national of the United States and the Netherlands. I speak fluent Spanish and am on a continuous journey to improve my Dutch. I have a 3 ½ year old French Bulldog named Bruna Fiona de l’Avesnois (aka “Goomba”) who I’m absolutely obsessed with. My hobbies are cooking, baking & hosting, collecting and caring for houseplants and playing poker and board games. I love to travel and always look for an excuse to visit new places and eat local cuisine. I believe in giving back to the community and strive to always be either donating to or volunteering for something. A few weeks ago I made my 10th blood donation in the Netherlands at Sanquin, which I’m very proud of.”

“I decided that I wanted my next job to be back in operations, but this time at a smaller company with a strong sense of community, a big growth potential in future-looking technologies, and a product that is not environmentally harmful: Hello DENSsolutions!” – Carl Hansen

Get to know Carl: Professionally

“I did my undergrad at Georgia State University in Spanish Language & Culture minoring in Business Administration. This program was a prerequisite for the International MBA Program where some courses and the professional internship must be done in a Spanish-speaking country. I also hold several professional certifications: CSCP & CPIM from the Association for Supply Chain Management; Lean Six Sigma Green Belt from SABIC; Teacher of English to Speakers of Other Languages (TESOL) from the University of Georgia, EHBO First Responder from the Dutch Red Cross, among others.

I started working at 14 at McDonald’s where I learned the importance of Spanish in communicating with customers and colleagues. I also was introduced to McDonald’s world-class operational procedures and quality control mechanisms. From the age of 14 to 21 I was continuously employed part-time at restaurants while I studied. Those experiences ultimately inspired me to choose the aforementioned university path. In my late teens and early twenties I backpacked extensively through Latin America which opened my eyes to the lack of resources and education many communities struggle with. That led me to an interest in non-profit work in microfinance and community business development, and ultimately to my MBA internship in Quito, Ecuador at CARE, where I worked on micro-tourism development and AIDS awareness programs in rural indigenous communities. 

After CARE I wanted to stay in South America but couldn’t find full time work in non-profit so I moved to Bogota, Colombia to teach at EAN University, in hopes that academia could also be a meaningful way to serve the community. The university environment very fortunately brought me in contact with many high-profile Colombian business leaders and politicians which ‘re-inspired’ me to get back into corporate life, moving away from non-profit and academia. One of these contacts was a recruiter for SABIC based in the Netherlands who offered me a supply chain position in Bergen op Zoom. So together with Lina we packed our bags and set out on the Dutch adventure. I worked at SABIC for just over 2 years as a Demand Planner where I earned my APICS and Six Sigma credentials. I left SABIC to join HYVA as its Global Sales & Operations Planning Manager where I worked for 3.5 years improving supply chain operations and cross-functional collaboration. I sidestepped from that role into a junior financial controller position to strengthen my financial acumen. After 3.5 years in finance (and 7 years at Hyva) I felt I had learned what I needed about finance and contributed as much as I could to the supply chain function. I decided that I wanted my next job to be back in operations, but this time at a smaller company with a strong sense of community, a big growth potential in future-looking technologies, and a product that is not environmentally harmful: Hello DENSsolutions! I feel thankful and blessed to be here and look forward to growing together with this great group of people and products.”

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Radboudumc expands its bio-research capabilities with newly installed DENSsolutions Stream system

Radboudumc expands its bio-research capabilities with newly installed DENSsolutions Stream system

We are excited to announce that DENSsolutions has installed a Stream system at the renowned Radboud University Medical Center (Radboudumc) in Nijmegen, the Netherlands. In this article, we interview Luco Rutten, PhD Candidate at Radboudumc, to learn more about the institute’s electron microscopy center, the team’s research direction and the pivotal role our Stream system will play in advancing their bio-research initiatives.

What is the Radboudumc Electron Microscopy Center known for?

“The Radboudumc Electron Microscopy (EM) Center, established in 2019 under the leadership of Dr. Anat Akiva and Prof. Dr. Nico Sommerdijk, operates as part of the RTC Microscopy within Radboud University Medical Center in Nijmegen, The Netherlands. Specializing in cutting-edge imaging and analysis techniques, including cryo-correlative light electron microscopy (cryo-CLEM), the EM Center serves users from both academia and industry. Notably, the center is equipped with a recently installed 200 kV Thermo Fisher Scientific TALOS F200C-G2 transmission electron microscope, featuring a Falcon 4i Direct Electron Detector, segmented STEM detector and EDS detector.”

What type of applications are the EM Center’s users interested in using Stream for?

“Since the Electron Microscopy Center is part of the University Medical Center, we are especially interested in using Stream to study biological and biomimetic processes under relevant conditions. For instance, the aggregation of protein-calcium complex and the biomineralization of organic scaffolds such as collagen mimicking health and disease. By adding the dynamic information from liquid phase EM to our cryo-CLEM workflow, we can unravel the mechanisms at the nanoscale of life.”

What particular features of Stream stood out to you?

“With our aim to study biological processes, the ability of the Stream system to seamlessly approach physiological conditions is of great importance. Since life occurs at 37 °C, precise control over the temperature is critical. Moreover, with Stream we are able to control liquid flow, enabling us to work with concentrations very close to physiological conditions. Additionally, we often deal with hybrid systems composed of both organic and inorganic materials, which can limit the contrast. By controlling the bulging of the windows through adjusting the front and back pressure, we’re able to reduce the liquid thickness as much as possible.

Could you tell us a bit more about the funding granted to acquire the systems?

“Prof. Dr. Nico Sommerdijk, the lead PI of the project titled ‘In Situ Imaging of Biological Materials with Nanoscale Resolution using Liquid Phase Electron Microscopy’, was awarded the NWO-groot grant of 1.5 million euros by the Dutch Scientific Organization to acquire state-of-the-art equipment for liquid phase electron microscopy to study biological processes. Part of this grant was used to acquire the Stream system. The aim of the program is to establish a globally unique facility dedicated to liquid phase electron microscopy on biological materials. The integration of the latest developments in software, hardware and sample preparation techniques will broaden the range of biological materials that can be investigated.”

In your experience so far, how have you found working with Stream?

“Operating the Stream system becomes quite routine after working with it a couple of times. The recent workshop organized by DENSsolutions for Stream users (see image below) provided a valuable opportunity to learn from experts like Dr. Hongyu Sun, DENSsolutions Senior App Scientist, and exchange experiences in working with the holder with other participants.

From left to right: Dr. Hongyu Sun (DENSsolutions), Luco Rutten (Radboudumc), Yannick Rutsch (FZ Jülich) and Rebecka Rilemark (Chalmers University of Technology)

Luco Rutten
PhD Candidate |  Electron Microscopy Center, Radboudumc

Luco Rutten received his Master’s degree in Chemistry and Chemical Engineering from the Eindhoven University of Technology. He is in his last year of his PhD at \Radboudumc under the supervision of Dr. Elena Macías-Sánchez and Prof. Dr. Nico Sommerdijk. As part of the Biomineralized Tissues group and the Electron Microscopy Center, he is using advanced electron microscopy to study bone mineralization mechanisms.

Discover the team’s publications:

 

Learn more about Stream:

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Meet our new colleagues Dr. Andrés Alvarez and Zhichao Liu

Meet our new colleagues Dr. Andrés Alvarez and Zhichao Liu

We are excited to announce the expansion of our team with two new wonderful colleagues: Andrés, our System Architect (Precision Engineer), and Zhichao, our Field Service Engineer.

DENSsolutions Eva Bladt

We are thrilled to introduce two of our newest colleagues who, just like the rest of our team, exemplify our commitment to innovation and excellence: Dr. Andrés Alvarez and Zhichao Liu. Dr. Andrés Alvarez takes the helm as our System Architect (Precision Engineer), who will play a key role in designing the architecture that underpins our cutting-edge solutions, from design all the way to implementation. With an extensive background in mechanical engineering, Andrés brings a unique blend of technical expertise and a creative touch to his projects. His role is instrumental in ensuring and boosting the reliability, robustness and ease-of-use of our solutions by incorporating top-notch precision engineering practices.

We are also thrilled to welcome Zhichao Liu, our new Field Service Engineer, who will play a crucial role in the installation, service and repair of our in situ electron microscopy solutions, both globally and remotely. With a background in electrochemistry and micro- and nano-engineering/science, and experience in providing high-level training for microscopy techniques such as atomic force microscopy (AFM) and Raman microscopy, Zhichao is well-equipped as our new Field Service Engineer to ensure that our valued customers have all the support they need. In this article, we invite you to get to know Andrés and Zhichao better, delving into their background, education and experience as well as their role at DENSsolutions.

Meet Dr. Andrés Alvarez

“My name is Andrés Alvarez, and I come from Bogotá, Colombia. I was born in 1981, the youngest of three siblings. From an early age, I was fascinated with household devices, often taking them apart and putting them right back together. This early curiosity, coupled with the unwavering support of my parents, sparked my lifelong passion for science and engineering. I studied Mechanical Engineering at Universidad Nacional de Colombia, broadening my technical perspective with courses in product design, automation and electrical engineering. As I neared the end of my undergraduate studies, I contemplated a career in academia and dreamed of pursuing further studies abroad. However, a unique opportunity arose when I started working for Alfagres, a notable manufacturer of ceramic tile products and paints. At Alfagres, I was focused on developing production equipment. But my academic dreams were not entirely sidelined as I received a scholarship to pursue my master’s degree in Mechanical Engineering through the Erasmus Mundus program. This led me to study at the renowned universities of Universitat Politècnica de Catalunya and Ecole Nationale de Sciences Appliquées de Lyon.

“Outside of my professional journey, I have many interests – I grew up liking the television, music and videogames of the eighties and nineties, with a lot of influence from my older brother. I’ve also always enjoyed fantasy and science fiction novels. Nowadays. I have a wide-ranging taste in music and enjoy playing video games, musical instruments and board games.” – Dr. Andrés Alvarez

My pursuit of knowledge then led me to a PhD in the Netherlands at Delft University of Technology, where I was part of the Intelligent Mechanical Systems group, focusing on the ‘automatic generation of control software for mechatronic systems.’ This project allowed me to collaborate with high-tech companies, expanding my knowledge of system architecting and model-based design. In 2011, I successfully defended my PhD thesis, titled ‘Architecture-centric design: Modeling and applications to control architecture generation.’ Stepping away from academia and transitioning to industry instead, I first worked at Sonion, developing miniature devices integrating electro-acoustical sensors and actuators for the hearing-aid industry. Then I joined the Dutch Ophthalmic Research Center as a Systems Architect, where I contributed to the development of the EVA platform for ophthalmic surgery systems. This product interfaces with a wide range of surgical instruments, providing approximately 10 different surgical functions. It also features a graphical user interface for real-time adjustments, ensuring a seamless match with the surgery plan and addressing any unexpected situations in the operating room. Now, at DENSsolutions, I’m excited to embrace new challenges in the complex and dynamic field of in situ microscopy. This role involves seeking innovative solutions to product architecture, and I believe that my diverse background in academia and industry has equipped me with a unique set of skills to tackle the cutting-edge challenges of this industry.”

Meet Zhichao Liu

“My name is Zhichao Liu, and I was born and raised in China. My scientific journey began at Ocean University of China, where I pursued a degree in polymer materials and engineering. My inspiration to undergo this degree came from understanding the endless potential of polymers in reshaping the future. My studies covered diverse subjects, ranging from the intricacies of mathematics and physics to the fascinating world of polymer materials and electrochemistry. After finishing my bachelor’s degree, I moved to the Netherlands to pursue a master’s degree in Electrochemistry and Nanoscience at Leiden University. It was specifically during this time that I uncovered my passion for electrochemistry and micro- and nano-engineering, setting the course for many of my future endeavors. This passion led me to pursue a PhD in electrochemical sensor fabrication with micro and nano techniques at Delft University of Technology (TU Delft). During my doctoral journey, I successfully fabricated electrochemical sensor chips using inkjet printing methods. These cutting-edge chips are adept at monitoring a wide array of molecular levels within the human body, such as dopamine, glucose and tyrosine. Beyond research, I actively participated in various roles. One notable role I undertook was a Lab Instructor at the PME department’s chemistry lab at TU Delft, where I was responsible for providing comprehensive training to all masters, doctoral and post-doctoral students before they used the chemistry lab. I also needed to understand their research objectives, assisting them in devising experimental schemes and alerting them to potential risks and hazards.

“Aside from my professional life, one of my greatest hobbies is swimming, especially in the sea. Beyond my love for swimming, I’ve always had an appreciation for nature, immersing myself in it through hiking expeditions when I can. I also enjoy keeping myself busy with projects where I’m able to exercise my love for invention, so I’m often crafting various gadgets and devices at home. In fact, my latest project to date is designing and developing an electric-foil surfboard.” – Zhichao Liu

Additionally, at TU Delft I served as the instructor for equipment like the electrochemical workstation, and techniques like AFM and Raman microscopy. Moreover, my duties in this capacity included not only training users but also daily maintenance of the instruments, troubleshooting and coordinating repairs with the manufacturers. Importantly, it was during my tenure as a Raman instructor that I became familiar with DENSsolutions. I was particularly impressed to learn of the company’s dedication to technological innovation, successfully developing cutting-edge in situ solutions that hold a significant position in the market. As a Field Service Engineer at DENSsolutions, my primary objective is to ensure optimal performance and longevity of our in situ electron microscopy solutions. I’m committed to providing efficient installations, timely services and prompt repairs to maintain and enhance customer trust and satisfaction. Additionally, I aim to continually learn and gather feedback to appropriately address evolving customer needs, furthering the company’s reputation for excellence.“

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Introducing Lightning Arctic: Our latest In Situ TEM Cooling, Biasing & Heating solution

Introducing Lightning Arctic: Our latest In Situ TEM Cooling, Biasing & Heating solution

An interview with DENSsolutions Senior Product Manager Dr. Gin Pivak about our latest addition to the Lightning product family: Lightning Arctic.

DENSsolutions introduces its latest product: Lightning Arctic – an innovative in situ solution that can perform cooling, biasing and heating all in one system. In this article, we interview our Senior Product Manager Dr. Gin Pivak to learn all about Lightning Arctic, including its unique capabilities and wide application space.

1) What are the main application fields that will benefit from Lightning Arctic?

“There are numerous applications where Lightning Arctic can play an important role. The ability to cool a sample and apply electrical stimuli enables researchers to study low-temperature physics, reaching temperatures as low as 100 Kelvin. It can be utilized to investigate magnetic materials and nanostructures, superconductors, topological insulators, ferroelectrics and more. Additionally, the application of Lightning Arctic can be expanded to include beam-sensitive materials such as Li-ion batteries, organic superconductors and perovskite-based solar cells, where the cooling capability can prolong the material’s lifespan under the electron beam. Furthermore, the ability to perform electro and/or thermal experiments at high temperatures allows the Lightning Arctic system to be used in the fields of nanomaterials sintering and growth, metals and alloys, low-dimensional materials, resistive switching, phase-change materials, solid oxide fuel cells, piezoelectrics, solid-state batteries and so on.”

2) Has the system already been installed?

“Yes, the system has been installed at the Faculty of Engineering, Department of Materials at Imperial College London (ICL) in the UK. The main user of the Lightning Arctic system at ICL is Dr. Shelly Conroy, who is exploiting various ferroelectric and quantum materials at low temperatures and at atomic resolution.”

3) What are the main benefits of Lightning Arctic for users?

“Lightning Arctic brings forth numerous advantages for your in situ experiments:

1) Perform in situ cooling and heating experiments: A cooling rod inside the Lightning Arctic holder can transfer the ‘cold’ towards the tip of the holder where the MEMS-based Nano-Chip holding the sample is located. Once this cooling rod is connected to a detachable metallic cooling braid which is immersed in an external dewar filled with liquid nitrogen, the sample can be cooled inside the TEM down to liquid nitrogen temperatures. Aside from cooling, the Lightning Arctic holder also enables in situ heating experiments, where the temperature can reach 800 °C and even 1300 °C depending on the chip used.

2) Experience atomic imaging stability: The Lightning Arctic holder was uniquely designed to host a number of additional temperature controllers that work to stabilize the sample drift during cooling. One controller ensures the temperature equilibrium with the TEM while the other stabilizes the cold influx towards the sample. The usage of the external dewar that helps to minimize the liquid nitrogen bubbling ensures that atomic imaging with low sample drift can be achieved.

3) Continuous temperature control: Our state-of-the-art Heating and Biasing Nano-Chips enable the local manipulation of the temperature of the sample while not disturbing the cooling process of the holder. This means that you can achieve the fast setting of any user-defined temperature and the minimization of the image and focus shift when changing the temperature setpoint, all while ensuring atomic-scale imaging quality.

4) Achieve your required sample orientation: The double tilt Lightning Arctic holder allows tilting the sample in both alpha and beta directions of 10 – 25 degrees to find the required zone axis of the sample.

5) Perform in situ biasing experiments while cooling/heating: The Heating and Biasing Nano-Chips compatible with the Lightning Arctic holder contain biasing electrodes that can be used to apply and measure electrical signals either during cooling or during heating. Of course, the preparation of FIB lamellas on the Nano-Chips for electrical experiments is very crucial. There are already proven methods and tools developed for the Lightning system (like the DENSsolutions FIB stub) that can be used to prepare top-quality, short-circuit-free FIB lamellas on the Heating and Biasing chips for the Lightning Arctic system.

6) Wide compatibility of the sample carriers: Lightning Arctic has a similar Nano-Chip compatibility to the Lighting system, and works with Wildfire heating Nano-Chips and Lightning heating and biasing Nano-Chips. Moreover, the Lightning Arctic holder is also compatible with 3mm and lift-out TEM grids that can be used to study beam-sensitive materials at cryo-conditions without the need of using the Nano-Chips. This greatly expands the range of samples that the new in situ solution can work with.”

 

Read more about Lightning Arctic:

 

Download the Lightning Arctic brochure:

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DENSsolutions successfully installs both a Stream and Climate system at Cardiff University

DENSsolutions successfully installs both a Stream and Climate system at Cardiff University

From left to right: Oliver Mchugh and Dr. Thomas Slater from Cardiff University, Dr. Lars van der Wal and Alex Rozene from DENSsolutions

We are excited to announce that DENSsolutions has installed both a Stream and Climate system at the renowned Cardiff University in Wales, the United Kingdom. In this article, we interview Dr. Thomas Slater, Lecturer at Cardiff University, to learn more about the Cardiff Catalysis Institute Electron Microscope Facility, the team’s research direction and the pivotal role our Stream and Climate systems will play in advancing their research initiatives.

Can you tell me about the Cardiff Catalysis Institute Electron Microscope Facility?

“The Cardiff Catalysis Institute Electron Microscope Facility (CCI-EMF) is based at Cardiff University, one of Britain’s leading research Universities. The CCI-EMF is a new, world-class electron microscopy facility located in the University’s Translational Research Hub on its Innovation Campus. It houses an array of state-of-the-art imaging and analytical instruments designed around the study of heterogeneous catalysts and nano materials. The mission of the facility is to provide researchers in academia and industry with cutting-edge microscopy equipment, creating a Welsh hub for electron microscopy expertise and skills development.

In October 2022, we installed a 200 kV Thermo Fisher Scientific Cold-FEG Spectra 200. This aberration-corrected scanning transmission electron microscope (AC-STEM) is the first of its type in Wales. It is optimised for the study and analysis of heterogeneous catalysts and nanoparticles and is fitted with the Super-X EDS detector, Panther STEM detection system for HAADF/BF and iDPC imaging, Gatan’s Continuum ER EELS and Quantum Detectors Merlin detector. The facility also hosts a JEM-2100 LaB transmission electron microscope with a high-resolution Gatan digital camera and Oxford X-max EDS detector and a Tescan MAIA-3 field emission gun scanning electron microscope (FEG-SEM), which enables secondary electron (SE), in-beam SE, low-kV backscattered electron (BSE), in-beam BSE and scanning transmission electron microscopy (STEM) imaging capabilities.”

What type of applications are the users at CCI-EMF interested in using the Stream and Climate systems for?

“The Stream In Situ TEM Liquid + Biasing or Heating system will enable us to study liquid-phase reactions and follow the mechanisms of nanoparticle synthesis in solution. Nanoparticle growth and crystallization on the surface of metal oxide supports is of particular interest to us, along with catalyst stability in solution and the mechanisms of deactivation through leaching and particle migration.

The Climate In Situ TEM Gas + Heating system will allow the CCI researchers to conduct operando STEM, TEM and chemical imaging of heterogeneous catalysts under reaction conditions. We aim to develop an improved understanding of structure-activity relationships, oxidation and reduction processes, catalysts synthesis, catalyst stability and deactivation mechanisms. Crucially, we will be able to study changes in the structure and chemistry as a function of temperature, pressure and composition, improving our understanding of catalysed processes at or near real reaction conditions.”

What particular features of the DENSsolutions systems stood out to you?

“For us it was critical to have excellent thermal stability, a uniform heated zone and fast gas mixing at the cell to ensure reproducibility and correlation with our larger scale benchtop micro- reactors. Chemical compatibility with a wide range of reaction gases and catalyst materials was also important as we support a vast number of researchers across multiple research projects with very different experimental requirements.”

Could you tell us a bit more about the funding granted to acquire the systems?

“The system was purchased with European Regional Development Funding (ERDF) through the Welsh European Funding office (WEFO) and part-funded by The Wolfson Foundation. The funding enabled the CCI to establish its own EM facility through the purchase of advanced microscopes and equipment such as the DENSsolutions Stream and Climate systems. This capability enhances and strengthens the already outstanding catalyst research facilities of the CCI and our aim is to use this new capability to support the research needs of the University, our existing partners, local industry as well as develop new research strands.”

In your experience so far, how have you found working with Stream and Climate?

“The installation went very smoothly and was completed in a couple of weeks, including the 3 days of training. The hardware is robust, and the chip assembly relatively intuitive. We are able to have chips prepared, assembled, leak-checked and in the microscope within the space of a couple of hours which leaves the rest of the days free for experiments. The parameter control is made easy through the Impulse software workflow which guides you from start to finish. In fact, we were running experiments ourselves and generating data within a week of installation.”

Dr. Tom Slater
Lecturer |  Electron Microscopy of Catalytic Materials, Cardiff University

Dr. Tom Slater received his Ph.D. in Nanoscience from the University of Manchester, where he also did postdoctoral work in the Henry Moseley X-ray Imaging Facility. He then joined the electron Physical Sciences Imaging Centre (ePSIC) as an electron microscopy scientist. He was appointed as a Lecturer in Electron Microscopy of Catalytic Materials at Cardiff University in 2022, where his research focuses on imaging of heterogeneous catalysts.

Discover Dr. Slater’s publications:

 

Learn more about Stream:

Learn more about Climate:

 

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