Driving the field of LPEM forward at the Gordon conference

Driving the field of LPEM forward at the Gordon conference

Last month, our Stream Product Manager Gin Pivak, CTO Hugo Perez and Microsystems Engineer Tijn van Omme visited the Gordon Research Conference (GRC) on Liquid Phase Electron Microscopy (LPEM). They were there to inform the LPEM community about our Stream system which allows researchers to introduce an accurate and controlled liquid environment combined with in-situ heating or biasing possibilities.
We realized that most researchers were still assuming that all liquid holders for LPEM are still relying on the ‘bathtub’ style (i.e. pocket structure where the 2 chips are placed). This is far from ideal, as the liquid bypasses the nano-cell and it only flows towards the window by diffusion in a non-controlled and spontaneous way. Therefore, it was a big relief for the LPEM community to learn that our Stream system now enables the real benefits, like (a) accurately controlling pressure and flow over the window, (b) controlling membrane bulging (i.e. controlling the liquid thickness) to enable higher resolutions, (c) enabling meaningful results in structure determination and analytical microscopy studies (e.g. EDS, EELS, electron diffraction), (d) controlling and mitigating bubble formation and most importantly, (e) reproducible experiments.
The Gordon Research Conferences are a special type of conference aimed at advancing frontier research. The idea is to bring all the relevant people in the field together to discuss and present (unpublished) results and to talk about the future directions of the field. All the major players in the field were present, and there was a lot of time for interaction. This created an open atmosphere, in which knowledge was shared and collaborations were established.
It became clear that the Liquid Phase Electron Microscopy community is maturing. LPEM offers a unique way for scientists to obtain information within a wide range of fields, including nanoparticle synthesis, self-assembly, corrosion, batteries, semicon, proteins and cells. However, compared to Cryo-EM, the field is still in its early days. A number of challenges still exist before results will be reproducibly accepted by non-microscopist communities. For example how to deal with the influence of the e-beam and how to control other influencing parameters.

‘Bathtub’ style LPEM system. Liquid bypasses the Nano-Cell and flows toward the window in a non-controlled and spontaneous way.

DENSsolutions Stream LPEM system. On-chip microfluidic channel enables full control over the liquid flow and pressure, thus the liquid-sample interaction.

On the first day of the conference, our CTO gave a presentation about the Stream Liquid Biasing and Liquid Heating system which resonated well amongst the attendees. The on-chip microfluidic channel in combination with the pressure control in the Stream system aligns well with the current and future demands of the field, as it enables control over the flow and liquid layer thickness.

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1st European Climate User Meeting

1st European Climate User Meeting

Where we find out how our solutions accelerate research and how we can adapt to new challenges.

DENSsolutions team members together with customers from FHI Berlin, DTU Nanolab Kgs. Lyngby, ER-C Jülich, EMAT Antwerp, ETH Zürich, Johnson-Matthey Didcot, University of Limerick, Trinity College Dublin and Queen’s University Belfast.
A little over 3 years ago, the first Climate in situ gas & heating systems were installed by DENSsolutions at customer sites. Therefore, the time has come to evaluate the results obtained so far by all our European customers and to share experiences. A 2-day meeting was held in Delft, the Netherlands on 5th & 6th June 2019 to provide an open forum for both users and the DENSsolutions team to share their results and suggestions.
Dr. Michele Conroy and Dr. Jennifer Cookman from the University of Limerick sharing their future plans for Climate experiments.

Presentations and discussions

Each Climate user gave a presentation on: their in situ gas & heating research, other research using the Climate system in their departments, and plans for future research.The topics covered included catalyst research on nano-particles, carbon nano-tube growth, and materials science on lamella-type samples. Our team members also gave presentations on our latest product development and newest applications.

Dr. Armand Beche (center) from EMAT Antwerp
Dr. Xing Huang (right) from ETH Zurich
We value the experience and feedback that our users from different institutes and companies, as well as DENSsolutions team members, brought to the discussions. Our discussions were dynamic and covered not only in situ TEM but also experiments that used the Climate Nano-Reactor in other environments such as a Beamline or an X-ray microscope.
Dr. Manfred Schuster from Johnson Matthey sharing insights from their customized beamline experiment
During the conference, new ideas, theories and product feedback were shared so we left with a list of possible improvements for our solutions as needed by the people who use them. These included: ease-of-use items, improvements on MEMS chips, tools to improve sample drop casting, and ideas on how to improve gas & heating control.
Dr. Thomas Hansen DTU explaining on the importance of low dose imaging.

Continuing the conversation

All the participants agreed that we should continue these discussions to improve both in situ TEM research and the tools that facilitate it. DENSsolutions will enable these conversations as part of an online environment as well as by organizing new Climate user meetings. Furthermore we see possibilities to organize forums like this in the future for other products and for users from other regions.

Ronald Marx MSc, DENSsolutions
Our Climate Product Manager Ronald Marx commented at the end of the 2-day meeting:
“It was a great pleasure for me to host all these Climate users in Delft and engage in discussions that reveal both the current and the potential new benefits of doing in situ research with the system’.

Download the Climate Brochure

For more information on features and specifications.

Where we find out how our solutions accelerate research and how we can adapt to new challenges.

DENSsolutions team members together with customers from FHI Berlin, DTU Nanolab Kgs. Lyngby, ER-C Jülich, EMAT Antwerp, ETH Zürich, Johnson-Matthey Didcot, University of Limerick, Trinity College Dublin and Queen’s University Belfast.
A little over 3 years ago, the first Climate in situ gas & heating systems were installed by DENSsolutions at customer sites. Therefore, the time has come to evaluate the results obtained so far by all our European customers and to share experiences. A 2-day meeting was held in Delft, the Netherlands on 5th & 6th June 2019 to provide an open forum for both users and the DENSsolutions team to share their results and suggestions.
Dr. Michele Conroy and Dr. Jennifer Cookman from the University of Limerick sharing their future plans for Climate experiments.

Presentations and discussions

Each Climate user gave a presentation on: their in situ gas & heating research, other research using the Climate system in their departments, and plans for future research.The topics covered included catalyst research on nano-particles, carbon nano-tube growth, and materials science on lamella-type samples. Our team members also gave presentations on our latest product development and newest applications.

Dr. Armand Beche (center) from EMAT Antwerp
Dr. Xing Huang (right) from ETH Zurich
We value the experience and feedback that our users from different institutes and companies, as well as DENSsolutions team members, brought to the discussions. Our discussions were dynamic and covered not only in situ TEM but also experiments that used the Climate Nano-Reactor in other environments such as a Beamline or an X-ray microscope.
Dr. Manfred Schuster from Johnson Matthey sharing insights from their customized beamline experiment
During the conference, new ideas, theories and product feedback were shared so we left with a list of possible improvements for our solutions as needed by the people who use them. These included: ease-of-use items, improvements on MEMS chips, tools to improve sample drop casting, and ideas on how to improve gas & heating control.
Dr. Thomas Hansen DTU explaining on the importance of low dose imaging.

Continuing the conversation

All the participants agreed that we should continue these discussions to improve both in situ TEM research and the tools that facilitate it. DENSsolutions will enable these conversations as part of an online environment as well as by organizing new Climate user meetings. Furthermore we see possibilities to organize forums like this in the future for other products and for users from other regions.

Ronald Marx MSc, DENSsolutions
Our Climate Product Manager Ronald Marx commented at the end of the 2-day meeting:
“It was a great pleasure for me to host all these Climate users in Delft and engage in discussions that reveal both the current and the potential new benefits of doing in situ research with the system’.

Interested in the Climate system?

Download the Climate Brochure

For more information on features and specifications.

MPM4 conference, Zhejiang University

MPM4 conference, Zhejiang University

DENSsolutions presence at the 4th International Conference on Materials Microstructure and Performance (MPM4).

Zhejiang University and DENSsolutions have a long standing relationship. In 2013 already, the prestige Zhejiang University became one of our first clients. Choosing the wildfire system for its high stability at elevated temperatures. Later they also acquired the Lightning Biasing system and the Climate combined Gas and Heating system. Using the Climate system they published several high impact publications like the ones, among others, on Nanoparticles and Pd Nanocrystals.  
2015 Presentation by by DENSsolutions at Zhejiang University Conference
MPM4 conference, Zhejiang University May 15-19
This conference, organized by School of Materials Science and Engineering, will focus on the latest developments in In situ Electron Microscopy, Biological materials, Semiconductor optoelectronic materials and Energy storage materials and battery technology.
Zhejiang University in collaboration with our distributor DENS ALTA technologies will give a demonstration of the Climate In Situ Gas and Heating system on the 16th of May in their Center of Electron Microscopy.
Click here for more information about Climate

Dr. Qiang Xu

Presentation: Stream – New generation of In Situ liquid system
Also on the 16th of may, our Vp of Business Development, Dr. Qiang Xu,  will give a presentation on our Stream In Situ liquid and biasing system. Explaining how we at DENSsolutions achieve to create a reliable and user friendly solution taking in to account the complexity of hardware, software and methodology.
Click here for more information about Stream

DENSsolutions presence at the 4th International Conference on Materials Microstructure and Performance (MPM4).

Zhejiang University and DENSsolutions have a long standing relationship. In 2013 already, the prestige Zhejiang University became one of our first clients. Choosing the wildfire system for its high stability at elevated temperatures. Later they also acquired the Lightning Biasing system and the Climate combined Gas and Heating system. Using the Climate system they published several high impact publications like the ones, among others, on Nanoparticles and Pd Nanocrystals.  
2015 Presentation by by DENSsolutions at Zhejiang University Conference
MPM4 conference, Zhejiang University May 15-19
This conference, organized by School of Materials Science and Engineering, will focus on the latest developments in In situ Electron Microscopy, Biological materials, Semiconductor optoelectronic materials and Energy storage materials and battery technology.
Zhejiang University in collaboration with our distributor DENS ALTA technologies will give a demonstration of the Climate In Situ Gas and Heating system on the 16th of May in their Center of Electron Microscopy.
Click here for more information about Climate

Dr. Qiang Xu

Presentation: Stream – New generation of In Situ liquid system
Also on the 16th of may, our Vp of Business Development, Dr. Qiang Xu,  will give a presentation on our Stream In Situ liquid and biasing system. Explaining how we at DENSsolutions achieve to create a reliable and user friendly solution taking in to account the complexity of hardware, software and methodology.
Click here for more information about Stream

STEM Meeting, Tianjin University of Technology

STEM Meeting, Tianjin University of Technology

DENSsolutions presence at STEM meeting, Tianjin University of Technology

We are proud to be among one of the leading high tech companies invited for this meeting. In 2016, the prestige Tianjin University of Technology became the first client in China to use a Stream In Situ Liquid and Biasing system. At the same time they became a DECEM (DENSsolutions essence center of electron microscopy) and just recently they created a big impact with their new discoveries on single atom catalyst, with a significant contribution of Prof. Jun Luo, using our Climate In Situ Gas and Heating system.
Tianjin city
STEM Meeting, Tianjin University of Technology May 16-18
This meeting, organized by our dear customer Prof. Jun Luo, will host 40 well-known experts and scholars in electron microscopy and materials science to discuss the latest developments in the fields of materials science, applied physics, chemistry, and chemical engineering.
Dr. Hongyu Sun
Stream Demo: In Situ TEM Liquid + Heating or Biasing
On the 18th of may, our Application Specialist Dr. Hongy Sun wil give a demonstration of our latest system which allows for high resolution liquid phase TEM. With a unique level of control over a.o. the membrane bulging and liquid flow rate. Dr. Hongyu will demonstrate the sytem showing controllable electro deposition of copper layers in liquid.
Click here for more information about Stream

Dr. Qiang Xu

Presentation: Stream – New generation of In Situ liquid system
Also on the 18th of may, our Vp of Business Development, Dr. Qiang Xu will give a presentation on the Stream system. Explaining how we at DENSsolutions achieve to create a reliable and user friendly solution taking in to account the complexity of hardware, software and methodology.
Click here for more information about Stream

DENSsolutions presence at STEM meeting, Tianjin University of Technology

We are proud to be among one of the leading high tech companies invited for this meeting. In 2016, the prestige Tianjin University of Technology became the first client in China to use a Stream In Situ Liquid and Biasing system. At the same time they became a DECEM (DENSsolutions essence center of electron microscopy) and just recently they created a big impact with their new discoveries on single atom catalyst, with a significant contribution of Prof. Jun Luo, using our Climate In Situ Gas and Heating system.
Tianjin city
STEM Meeting, Tianjin University of Technology May 16-18
This meeting, organized by our dear customer Prof. Jun Luo, will host 40 well-known experts and scholars in electron microscopy and materials science to discuss the latest developments in the fields of materials science, applied physics, chemistry, and chemical engineering.
Dr. Hongyu Sun
Stream Demo: In Situ TEM Liquid + Heating or Biasing
On the 18th of may, our Application Specialist Dr. Hongy Sun wil give a demonstration of our latest system which allows for high resolution liquid phase TEM. With a unique level of control over a.o. the membrane bulging and liquid flow rate. Dr. Hongyu will demonstrate the sytem showing controllable electro deposition of copper layers in liquid.
Click here for more information about Stream

Dr. Qiang Xu

Presentation: Stream – New generation of In Situ liquid system
Also on the 18th of may, our Vp of Business Development, Dr. Qiang Xu will give a presentation on the Stream system. Explaining how we at DENSsolutions achieve to create a reliable and user friendly solution taking in to account the complexity of hardware, software and methodology.
Click here for more information about Stream