In Situ TEM Liquid + Biasing or Heating

Controlled dynamics in the liquid state

Liquid phase microscopy has become increasingly popular, as it provides new insight into important processes of various research topics within material science, chemistry and biology.
The Stream In Situ Liquid Solution radically changes the way experiments in liquid are carried out. The innovative technology brought to you by DENSsolutions offers for the first time

  • Accurate flow and pressure control
  • Controlled membrane bulging
  • Extended experimental flexibility

Stream Application Fields

Nano-Cell

Stream Nano-Cell

The core of the Stream system is our patented Nano-Cell. The Nano-Cell consists of a top (A) and bottom chip (B), which together form a sealed compartment that enable you to safely perform liquid experiments inside the TEM.

The top and bottom chip both contain electron transparant windows (C&D) which enable you to image your sample. The sample is located on the bottom window (D) and can be exposed to heating or biasing, depending on the type of bottom chip you use.   

Next generation liquid control

A big step forward in the field of Liquid Phase Electron Microscopy (LPEM)

Our next generation Stream system now allows the users full control over their sample to liquid interaction. In this new chip design, the liquid directly enters the chip through an inlet, is guided over the sample by a defined channel and leaves the chip through an outlet.

Combined with the ability to regulate the inlet and outlet pressure, the user is now able to control the speed, pressure and direction of the liquid inside the cell.

The flow control of the Stream system is a big step forward compared to our previous generation LPEM system Ocean which uses a ‘bathtub’ design that is comparable to most LPEM systems on the market. In this design, the Nano-Cell is placed inside a pocket and liquid can enter the cell from all sides.

There is no control over the speed, pressure and direction of the liquid inside the cell because they are independent from the speed, pressure and direction of the liquid in the pocket surrounding the cell.

Our next generation Stream system now allows the users full control over their sample to liquid interaction. In this new chip design, the liquid directly enters the chip through an inlet, is guided over the sample by a defined channel and leaves the chip through an outlet.

Combined with the ability to regulate the inlet and outlet pressure, the user is now able to control the speed, pressure and direction of the liquid inside the cell.

Pressure-based liquid pump

Gain full fluidic control 

The pressure-based liquid pump provides you with full control over the experiments

The new Nano-Cell

Controlled liquid environment within the microscope

The Stream Nano-Cells change radically the way experiments in liquid are performed.

Features

  • Defined liquid channel and no dead volumes
  • Pressurized inlet and outlet to accurately define pressure and flow rate, independently
  • Drastically reduced bulging for easier imaging

Modular Sample Holder

Ensure a clean experiment with a removable tip & tubing

Once the Nano-Cell is placed into the self-aligning precision slot within the Sample Holder tip, the O-rings and lid are sealed and the system is ready for vacuum testing. As the tip is removable, the internal liquid tubing can be replaced at any time to avoid clogging/cross-contamination and can be cleaned.

Stream brochure

Download the Stream brochure

For more information on workflow, applications and specifications.

Contact us

Feel free to contact us with any further questions.

Request a Demo or Quote

Request a quotation or demonstration at your lab.